What is Human Rabies? Symptoms, Causes, and its Treatment

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What is Rabies?

Rabies caused by RABV genotype 1 is one of the most prevalent deadly illnesses in the world. In Europe, Asia, and Africa, it is primarily connected with dog bites, but in the Americas, it is related to bats. Two-thirds of patients infected with dog RABV variations exhibit the characteristic symptoms of furious rabies (fluctuating consciousness and altered mental status, phobic or inspiratory spasms, and autonomic stimulation signals). The remaining third develop paralytic rabies, which is similar to Guillain-Barré syndrome, although progression to coma, myoedema, and bladder incontinence distinguish these two conditions. Rabies caused by bat RABV variations exhibits unique characteristics, including focal brainstem indications, myoclonus, hemichorea, and Horner’s syndrome symptoms.

Symptoms of Human rabies

Human rabies
Symptoms of human rabies

The first signs of rabies may look a lot like the flu and last for a few days.

Some of the later signs and symptoms could be:

  • Fever \Headache
  • Nausea
  • Vomiting
  • Agitation
  • Anxiety
  • Confusion
  • Hyperactivity
  • Trouble swallowing
  • Excessive salivation
  • Trying to drink fluids brings on fear because it’s hard to swallow water.
  • When air is blown on the face, it causes fear.
  • Hallucinations
  • Insomnia
  • Partial paralysis

If you’ve been bitten by an animal, or think one you’ve encountered might have rabies, you should see a doctor every once. You and your doctor can decide whether or not you need rabies prophylaxis based on the extent of your injuries and the circumstances of your exposure.

If you suspect you’ve been bitten, go to the hospital anyhow. A bat that flies into your bedroom at night can sneak up on you and bite you while you’re sleeping. Be concerned that you’ve been bitten if you wake up to find a bat in your room. You should also assume that a person who is too young or too disabled to communicate that they were bitten by a bat has been bitten if you come across a bat in their vicinity and they show signs of having been bitten.

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Causes of rabies

Human rabies
Causes of human rabies

An infection with the rabies virus results in rabies. The virus is transmitted from animal to animal through their saliva. Animals carrying the virus can infect other animals and humans by biting them. Rarely, rabies can be transmitted when contaminated saliva enters a cut or other open sore, or when it touches mucous membranes like the lips, nose, or eyes. If an infected animal licked an open wound on your body, this may happen.

Infectious rabies-carrying animals

Rabies can be transmitted to humans from any mammal (an animal that nurses its young). Rabies is most commonly spread to humans via the following animals:

Domesticated and domesticated animals

  • Cats \Cows
  • Dogs
  • Ferrets
  • Goats
  • Horses

Wild animals

  • Bats
  • Beavers
  • Coyotes
  • Foxes
  • Monkeys
  • Raccoons
  • Skunks
  • Woodchucks

Transplant recipients who received an infected organ or tissue have been exposed to the virus on infrequent occasions.

Rabies Postexposure Prophylaxis (PEP)

Human rabies immune globulin (HRIG) and the rabies vaccine are administered on the day of exposure as part of postexposure prophylaxis (PEP), followed by additional vaccinations on days 3, 7, and 14. Postexposure prophylaxis (PEP) always entails the injection of both HRIG and rabies vaccination for those who have never been immunized against rabies before. Whether a bite or non-bite exposure occurred first, HRIG and vaccination are the recommended courses of action.

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Rabies Prevention

In pets

You can prevent rabies in your pet in several ways.

  • Keep your cat, ferret, or dog up-to-date on their rabies vaccines by taking them on regular doctor visits.
  • Second, keep your pets under control by restricting cats and ferrets to the inside and keeping canines on a leash at all times.
  • Third, spay or neuter your pets to help control the overpopulation of animals that may not be getting the care they need or the necessary vaccinations.
  • Last but not least, if there are any strays in your area, contact animal control to have them removed.

In Humans

  • Know your risk for rabies and what to do if you come into touch with an animal. Although raccoons, skunks, bats, and foxes account for the majority of rabies cases in the United States, any mammal can contract the disease. Don’t approach any wild creatures, particularly those that appear to be hurt. Don’t handle an injured animal; instead, call the authorities for help.
  • Find out if rabies is present in dogs or wildlife at your location before travelling internationally. Rabies is still common in many countries outside the United States.
  • Preventing rabies in pets is also crucial in reducing the number of human rabies cases, as pets can contract the disease from wild animals and subsequently transmit it to people.
  • All cases of human rabies can be prevented with timely treatment if exposure to a rabid animal occurs. Consult a doctor if you have been bitten, scratched, or are unsure if you need PEP.

How is rabies diagnosed?

The direct fluorescent antibody (DFA) test detects rabies virus antigens in brain tissue and is used to diagnose the disease in animals. Multiple examinations of human subjects are needed. The prompt provision of postexposure prophylaxis relies on a laboratory diagnosis of rabies in humans and animals that is both rapid and accurate. A rabid animal can be identified and the appropriate medical personnel can be notified by a diagnostic laboratory within a few hours. If the animal is not rabid, the results from the laboratory may prevent the patient from experiencing unnecessary physical and psychological suffering as well as financial costs.

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How to treat rabies           

There is currently no cure for rabies once symptoms appear. The incubation period for death is 7–14 days after the onset of symptoms. If you suspect you have been exposed to rabies, you should immediately contact your doctor or go to the emergency room. When you start feeling sick, it’s already too late.


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